A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
This trial will evaluate the efficacy and safety of various therapies in participants with Stage IB, IIA, IIB, IIIA, or selected IIIB resectable and untreated NSCLC tumors that meet protocol-specified biomarker criteria.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony histopatologicznie rak płuca (niedrobnokomórkowy) w wczesnym stadium (IB, IIA, IIB, IIIA lub wybrany IIIB)
- •Nowotwór można całkowicie usunąć chirurgicznie
- •Nowotwór powinien być widoczny na tomografii komputerowej (CT) jako zmiana typu stałego lub częściowo zacienionego, nie całkowicie mlecznosiwy
- •Badanie genetyczne wykazało co najmniej jedną z następujących zmian: fuzję ALK, fuzję ROS1, mutację BRAF V600, fuzję RET, obecność PD-L1 na co najmniej 1% komórkach nowotworu lub mutację KRAS G12C
- •Wykonane badania obrazowe (CT, PET, rezonans magnetyczny mózgu) w celu określenia zaawansowania choroby
- •Brak wcześniejszego leczenia tego nowotworu
- •Nowotwór nie rozprzestrzeniał się na przeponę, osierdzie, serce, duże naczynia czy przełyk
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 9, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (38)
City of Hope Comprehensive Cancer Center
Duarte, United States
City of Hope - Orange County Lennar Foundation Cancer Center
Irvine, United States
USC Norris Cancer Center
Los Angeles, United States
Cedars-Sinai Medical Center
Los Angeles, United States
University of California Los Angeles - Jonsson Comprehensive Cancer Center
Los Angeles, United States
The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange
Orange, United States
UC Davis Comprehensive Cancer Center
Sacramento, United States
UCSF Helen Diller Family CCC
San Francisco, United States
University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center)
Aurora, United States
Yale Cancer Center
New Haven, United States
MedStar Georgetown University Hospital (Lombardi Comprehensive Cancer Center)
Washington D.C., United States
Moffitt Cancer Center
Tampa, United States
Northwestern University
Chicago, United States
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, United States
Northwestern Medicine Cancer Center Delnor
Geneva, United States
Northwestern Medicine Cancer Center Warrenville
Warrenville, United States
Boston Medical Center
Boston, United States
Dana-Farber Cancer Institute
Boston, United States
University of Michigan
Ann Arbor, United States
Karmanos Cancer Institute - Farmington Hills/Weisberg Cancer Treatment Center
Farmington Hills, United States
Mayo Clinic
Rochester, United States
Ellis Fischel Cancer Center
Columbia, United States
Siteman Cancer Center - Washington University Medical Campus
St Louis, United States
Dartmouth Hitchcock Medical Center
Lebanon, United States
Laura and ISAAC Perlmutter Cancer Center at NYU Langone.
New York, United States
Columbia University Medical Center
New York, United States
Memorial Sloan Kettering Cancer Center
New York, United States
University Hospitals Cleveland Medical Center
Cleveland, United States
Ohio State University
Columbus, United States
AHN Cancer Institute ? Allegheny General Hospital
Pittsburgh, United States
Baptist Clinical Research Institute
Memphis, United States
Tennessee Oncology - Nashville
Nashville, United States
Kelsey Seybold Clnic
Houston, United States
University of Texas MD Anderson Cancer Center
Houston, United States
Baylor College of Medicine
Houston, United States
Lumi Research
Kingwood, United States
Virginia Cancer Specialists (Fairfax) - USOR
Fairfax, United States
Seattle Cancer Care Alliance
Seattle, United States
Trial contact
Reference Study ID Number: ML41591 https://forpatients.roche.com/
Fastest response: use the inquiry form. No email attachments. https://www.gene.com/contact-us/submit-medical-inquiry
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.
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