Efficacy and Safety of Simultaneous Integrated Boost Radiotherapy in HR/VHR Prostate Cancer With EPLNI
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The aim of this study is to evaluate the efficacy and safety of hypofractionated simultaneous integrated boost volumetric arc radiation therapy (SIB - VMAT) for high-risk and very high-risk localized prostate cancer in terms of: 1. Acute and late gastrointestinal and genitourinary toxicities. 2. Evaluate the efficacy in terms of early bPFS. 3. Dosimetric evaluation in terms of target coverage and organs at risk sparing
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Potwierdzony rozpoznaniem histologiczne adenocarcinoma prostaty
- •Rak klasyfikowany jako zaawansowany (wysoki lub bardzo wysoki stopień ryzyka) zgodnie z wytycznymi NCCN
- •Dobra funkcja pęcherza moczowego na początku leczenia
- •Przeprowadzone badania obrazowe: MRI prostaty, tomografia CT klatki piersiowej i brzucha, scyntygrafia kostna
- •Opcjonalnie badanie PET/CT aby wykluczyć przerzuty na całym ciele
✗ Disqualifies
- •Wcześniejsza radioterapia w obrębie miednicy
- •Historia choroby zapalno-obturacyjnej jelit lub aktywne zapalenie odbytnicy
- •Przerzuty nowotworu na inne narządy
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 9, 2026
- Sex
- Male only
Therapies / drugs in trial
Locations (3)
Faculty of Medicine, Ain Shams University
Cairo, Egypt
Faculty of Medicine - Menoufia University
Shibīn al Kawm, Egypt
Faculty of Medicine - Sohag University
Sohag, Egypt
Trial contact
Mohamed Alhefny, MD
Ahmed Sohaib, MD
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/10/2026.
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