This is a first-in-human Phase 1b, 2-part, multicenter open-label clinical study to evaluate safety and efficacy of a Nectin-4 radiopharmaceutical (\[225Ac\]Ac-AKY-1189) in patients with locally advanced or metastatic solid tumors and to establish the maximum tolerated dose (MTD) or maximum administered dose (MAD) and the recommended Phase 2 dose.
[64Cu]Cu-AKY-1189 (imaging)
1 clinical trials involving this therapy/drug
This is not medical advice - consult your oncologist
Descriptions are automatically translated with AI assistance. Always verify details in the original on ClinicalTrials.gov and consult your treating physician.
RecruitingPhase IBreast cancerLung cancerCervical cancerColorectal cancerBladder cancerHead and neck cancerTriple negative (TNBC)Hormone receptor positive (HR+)Metastatic / advanced
NCT07020117ClinicalTrials.gov ↗
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