Study Evaluating the Efficacy of KITE-753 Versus Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma After First-Line Therapy
This is not medical advice. AI-assisted translation — inaccuracies may occur. Always verify the original and consult your oncologist before taking any steps.
About the trial
The goal of this clinical study is to compare the study drug KITE-753 versus axicabtagene ciloleucel (axi-cel) in adult participants with relapsed or refractory (r/r) large B-cell lymphoma (LBCL) after one prior line of therapy. The primary objective of this study is to evaluate the efficacy of KITE-753 versus axicabtagene ciloleucel.
Original English text from ClinicalTrials.gov
Who can (and can't) join
✓ Qualifies
- •Diagnoza nawrotowego lub opornego chłoniaka B-komórkowego
- •Wcześniejsze leczenie nie powiodło się (choroba oporna na chemioterapię lub nawrót w ciągu 12 miesięcy)
- •Wcześniejsze leczenie zawierało przeciwciało anty-CD20 i chemioterapię z antracyklinami
- •Co najmniej jeden widoczny guz do zmierzenia
- •Brak dodatkowego leczenia między pierwszą terapią a włączeniem do badania (poza sterydami lub promieniowaniem lokalnym)
Simplified criteria — AI translation
Trial details
- Minimum age
- 18 Years
- Last updated (source)
- July 15, 2026
- Sex
- No restrictions
Therapies / drugs in trial
Locations (10)
City of Hope (City of Hope National Medical Center, City of Hope Medical Center)
Duarte, United States
Stanford University
Stanford, United States
Colorado Blood Cancer Institute
Denver, United States
Southeastern Regional Medical Center, Inc. dba City of Hope Atlanta
Newnan, United States
Henry-Joyce Cancer Clinic
Nashville, United States
St. David's South Austin Medical Center
Austin, United States
Epworth Healthcare
East Melbourne, Australia
Jewish General Hospital
Montreal, Canada
McGill University Health Centre
Montreal, Canada
CHU de Québec, Hôpital de l'Enfant-Jésus
Québec, Canada
Trial contact
Medical Information
Contact information from ClinicalTrials.gov. Contact in English.
Share this trial
Data from ClinicalTrials.gov. AI-assisted translation, last sync: 7/16/2026.
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